Human performance has biological limits.

Dr. Chelsea Matisz is a neuroscientist, keynote speaker, and science communicator whose work focuses on how modern environments interact with human biology to shape capacity, behavior, and performance. Her research background spans evolutionary biology, neuroscience, and gastrointestinal sciences, with advanced training in stress physiology and brain–body regulation.

Chelsea’s work examines how external demands and internal signals shape biological regulators that determine available energy, cognitive capacity, and behavioral flexibility. Drawing on neuroscience, stress biology, and gut–brain research, she explains why behavior changes under sustained load, why effort and motivation alone often fail, and what restores capacity in demanding environments.

Through talks, writing, and public engagement, Chelsea translates complex biology into clear, practical frameworks that help individuals and organizations work with human biology rather than against it. Her TEDxCalgary talk, The Ancestral Paradox, explores how ancient biological systems collide with modern life, and introduces a compassionate, science-based way to understand stress, performance, and adaptation.